Mary’s award-winning transdermal patches are born out of a commitment to accurate dosing through an advanced delivery method. The 2”x2” squares simply adhere to any venous part of the skin for 8-12 hours of unsurpassed, systemic relief. Discreet, convenient and reliable• Apply to any venous area of the skin for best results• Provides 8-12 hours of unsurpassed, systemic relief• High bioavailability• 15-30-minute uptake time